CMT1B

CMT1B

Demyelinating

Autosomal Dominant

Associated Gene

MPZ

Chromosome

1q23.3

Zygosity

Heterozygous

CMT1B is caused by autosomal dominant mutations in the MPZ gene. CMT disease severity and age-at-onset varies greatly, from very severe CMT to very mild, and symptom onset anywhere between infancy and late adulthood. Age at onset does not determine disease severity.

Rev. Date

1/10/21